Research tool · randomized trials

RoB2-AI

Prepare an AI-assisted, evidence-linked draft risk-of-bias assessment for a randomized trial using the Cochrane RoB 2 framework.

Upload a study and get an assessment draft

Open the RoB2-AI tool in ChatGPT.
Attach the full-text trial report. Add the protocol, trial registration, statistical analysis plan, and supplement when available.
Specify the outcome, timepoint, result, and effect of interest. RoB 2 judgments are result-specific.
Review each domain judgment, quoted evidence and source location against the uploaded documents; correct or mark unclear items before using the output.

Open RoB2-AI & upload study ↗

The upload and analysis happen in the linked ChatGPT tool, not on this website. ChatGPT sign-in may be required.

Method and knowledge base

RoB 2 is designed for randomized trials and assesses risk of bias in a specific result. The assessment should follow the correct RoB 2 variant and current signalling-question guidance; do not treat the output as a study-wide score or convert domain judgments into an arbitrary numeric total.

Cochrane RoB 2: current version and materials ↗ · RoB 2 tool and guidance ↗ · Cochrane Bias Methods ↗

Research support only. AI-generated judgments are drafts. Verify the study design, estimand, outcome, timepoint, supporting evidence, and current official guidance. The tool does not replace independent human appraisal or a second reviewer.

RoB2-AI is independently developed and is not affiliated with, sponsored by, approved by, or endorsed by Cochrane or the RoB 2 developers.